🔗 Share this article Antidepressant Medication Adverse Reactions Such as Body Weight, BP Changes Differ Based on Pharmaceutical Recent study provides robust evidence of the extensive range of antidepressant medication side effects. A comprehensive new research discovered that the unwanted effects of depression drugs differ considerably by drug. Some drugs led to decreased mass, whereas others caused weight gain. Cardiac rhythm and arterial pressure furthermore differed notably across treatments. Those encountering ongoing, intense, or worrisome side effects ought to speak with a physician. Latest research has discovered that antidepressant medication adverse reactions may be more extensive than earlier believed. The large-scale investigation, issued on October 21st, examined the influence of depression treatments on more than 58,000 participants within the initial two months of commencing treatment. These scientists analyzed 151 research projects of 30 pharmaceuticals frequently employed to address clinical depression. Although not every patient experiences adverse reactions, several of the most common recorded in the study were changes in body weight, blood pressure, and metabolic indicators. There were significant differences across antidepressant drugs. For example, an eight-week course of agomelatine was connected with an average weight loss of around 2.4 kilos (approximately 5.3 lbs), while maprotiline individuals added almost 2 kg in the identical duration. Furthermore, marked fluctuations in heart function: fluvoxamine tended to decrease pulse rate, whereas another medication elevated it, creating a disparity of approximately 21 heartbeats per minute across the both treatments. Arterial pressure differed also, with an 11 mmHg variation observed between one drug and doxepin. Depression Drug Unwanted Effects Include a Broad Spectrum Clinical experts commented that the research's conclusions are not considered recent or startling to mental health professionals. "It has long been understood that various depression drugs range in their effects on body weight, BP, and additional metabolic measures," one professional commented. "However, what is remarkable about this investigation is the rigorous, comparison-based assessment of these variations throughout a broad array of bodily measurements utilizing findings from over 58,000 participants," this professional commented. The study offers strong support of the extent of adverse reactions, certain of which are more prevalent than other effects. Typical antidepressant medication adverse reactions may encompass: gastrointestinal symptoms (nausea, diarrhea, blockage) intimacy issues (reduced sex drive, anorgasmia) mass variations (increase or reduction, based on the drug) sleep disturbances (sleeplessness or sleepiness) mouth dryness, moisture, head pain Additionally, less common but medically important adverse reactions may include: elevations in blood pressure or cardiac rhythm (particularly with serotonin-norepinephrine reuptake inhibitors and some tricyclics) low sodium (notably in senior patients, with selective serotonin reuptake inhibitors and SNRIs) increased liver enzymes QTc lengthening (risk of arrhythmia, especially with citalopram and certain tricyclics) emotional blunting or lack of interest "A key factor to remember here is that there are several distinct types of antidepressants, which result in the varying unwanted medication side effects," a different professional commented. "Moreover, depression treatments can impact each person variably, and negative side effects can vary depending on the specific medication, amount, and personal factors such as metabolism or simultaneous health issues." While several adverse reactions, like variations in sleep, appetite, or energy levels, are quite frequent and commonly get better over time, different reactions may be less typical or continuing. Speak with Your Doctor Concerning Serious Adverse Reactions Depression drug unwanted effects may differ in seriousness, which could justify a modification in your medication. "A modification in antidepressant may be warranted if the patient experiences continuing or unacceptable side effects that fail to enhance with duration or supportive care," one specialist stated. "Furthermore, if there is an emergence of recently developed medical conditions that may be exacerbated by the present treatment, for instance high blood pressure, abnormal heart rhythm, or considerable increased body weight." Patients may furthermore consider speaking with your doctor concerning any absence of meaningful improvement in low mood or anxiety symptoms following an adequate trial period. An sufficient evaluation duration is generally 4–8 weeks at a treatment dosage. Patient choice is furthermore significant. Some people may choose to evade particular unwanted effects, including sexual dysfunction or {weight gain|increased body weight|mass addition